Pharmacogenomics

Pharmacogenomics combines the science of drugs (pharmacology) and the study of genes and their functions (genomics) to understand what are effective and safe medications for you.

Discover how your DNA influences your response to many prescribed and over-the-counter medications; this includes how you respond to a medication and your risk of unwanted side-effects.

Including specialist pharmacist advice, this test will identify medications that you should avoid completely.

This new science helps to avoid the usual trial and error approach to treatment.

 

Book a Pharmacogenomics Test

At your initial consultation we will discuss the test process and its benefits with you. 

We allow 30 minutes for this initial consultation so that we can take the swab in the same appointment. The fee for this initial consultation is £60, payable on booking. 

The remaining cost including the test, lab fees, and follow-up is £395. The balance is paid when you are in clinic.

Please select a date and time from the calendar, and then enter your details to book your initial appointment.

Book an Online Consultation
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Safe, private clinic

Our beautiful award-winning clinic is in the centre of Winchester and we look forward to welcoming you. Keeping you and others safe is our priority and so if you are unwell, please let us know in advance and we will make appropriate arrangements.

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Expert pharmacists

Pharmacists are specialists in medicines and their knowledge will help interpret the results of the test, and provide practical advice on which medicines will work best for you, which will have no effect and which medicines cause side effects.

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Private Pharmacy

We operate within a registered private pharmacy which means that we can discuss and provide any required treatments, tests or referrals as appropriate. You can also be assured that we work within a strict governance framework.

About pharmaco-genomics 

Particular genes in our DNA influence how well a drug works for you, and whether you will experience any side effects. Our genes affect how we absorb, metabolise, distribute and excrete a drug. They also affect drug targets within our bodies such as receptors, enzymes and ion channels (proteins which allow molecules to enter and leave a cell).

Identifying variations in these genes that affect how your body will respond to many common medicines will help predict which drug and dose is best suited for you.

Because our genes hardly change throughout our lifetime a pharmacogenomics test only needs to be done once.

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About this test
  • Discover how your DNA influences your response to many prescribed and over-the-counter medications
  • Identify how you respond to a medication and your risk of unwanted side-effects
  • Identify medications that you should avoid completely
  • Avoid the usual trial and error approach to treatment
  • Improve quality of life
  • A comprehensive clinically actionable DNA test for drug response
How does DNA affect your response to medicines?

Almost 99% of us carry at least one modification in our DNA that affects our response to many prescribed and over the counter medications, resulting in either unnecessary side-effects or it not working properly.

Selection and dose of medications should NOT be a ‘one size fits all’ approach.

Specific genes in our DNA code for specialised enzymes that metabolise our medications or that change how the medication reaches a specific part of the body. Variations in these genes can cause significant differences in enzyme performance resulting in a drug not working in quite the same way in one person as it does in another.

You may metabolise the drug too quickly meaning that it might all be gone before it has its intended effect and therefore the standard dose is not enough for you. Or, you may metabolise the drug too slowly, and it hangs around for too long, building up beyond safe levels in your body, leading to side effects. A medication that is safe for someone else may be dangerous for you, even at the same dose, and should be avoided.

FAQs

Do I have to take, or stop, any medication for the test?
You do not need to take any medication for the test. Do not stop any medication that you’re already taking. The test is designed to measure how your genes will react to certain medications, and not the presence of any medicine that is in your blood sample. Your current medication will also not have any effect on the test.

How much does it cost?
The test will cost £395 with a clinician ensuring the test is correctly performed. This includes the follow-up but does not include the initial consultation where a complete history is taken; the cost for this is £60.

How long does the test take/when will I get my results?
20 working days from receipt of your sample back in the laboratory. Reports will be emailed to our specialists here at REMEDI HEALTH to support intepretation.

What sample do I need to give?
A swab of the inside of your mouth. The cells lining the inside of your cheeks and oral cavity are called epithelial cells and contain your DNA.

How does the test work?
Cells from inside the lining of your mouth are called epithelial cells. Lightly removing the surface layer of these cells onto a swab provides the lab with a small amount of your DNA. The specific areas of your DNA that are responsible for how you metabolise drugs that are processed by the body through certain well defined metabolic pathways are then analysed.

How often do I have to take this test?
You only need to do this test once. Your genetic code doesn’t change, so you will always be able to refer to your test should you need to take any over the counter or prescription medication in the future.

Does it matter what time of the day I test?
Not at all. Only requirement is that you have not eaten or drunk anything for 30 minutes before taking your swab. The presence of food particles on your swab may prevent the test from working. Liquid can result in insufficient numbers of cells.

Will I be able to understand the results of the test, or will I need my GP to explain it to me?
The report is very informative and will require interpretation from our specialist Pharmacist. They will look at the report and help you make a decision in context with your medical history and overall health. They can also liaise with your GP. You must not attempt to change your regime based on your own interpretation.

Is this test only for people currently taking drugs for certain conditions, or can anyone do it?
Anyone, of any age, regardless of whether they are on drugs or not can do the test. The report is with you for life. It could be of huge benefit for you in the future and helping your Practitioner make decisions around what drugs to give you should you need them. The time, possible side-effects and even money saved from taking the right drug at the right dose from the outset is a huge benefit to us all.

Is the test reliable and does it have evidence to support it?
The field of pharmacogenomics has grown rapidly and there is more than sufficient evidence to support the routine use of PGx testing, especially for you if you are taking long term prescribed drugs. In a study done in the USA , almost two-thirds of people needed to have their drugs changed due to them experiencing unwelcome side effects. Almost all the recommended prescription changes were endorsed by their doctors.

Can we help you?

Our team are standing by to help you with any questions or queries that you may have. We can advise you on the best test, product or service for your requirements.